Elastin
From Wikipedia, the free encyclopedia
| elastin
| |
| Identifiers | |
| Symbol | ELN |
| Entrez | 2006 |
| HUGO | 3327 |
| OMIM | 130160 |
| RefSeq | NM_000501 |
| UniProt | P15502 |
| Other data | |
| Locus | Chr. 7 q11.1-21.1 |
Elastin is a protein in connective tissue that is elastic and allows many tissues in the body to resume their shape after stretching or contracting. Elastin helps skin to return to its original position when it is poked or pinched. Elastin is also an important load-bearing tissue in the bodies of mammals and used in places where mechanical energy is required to be stored.
Contents |
[edit] Composition
It is primarily composed of the amino acids glycine, valine, alanine, and proline.
Elastin is made by linking many soluble tropoelastin protein molecules, in a reaction catalyzed by lysyl oxidase, to make a massive insoluble, durable cross-linked array. The amino acid responsible for these cross-links is lysine.
Desmosine and isodesmosine are both found in elastin.
[edit] Locations in body
Elastin serves an important function in arteries and is particularly abundant in large elastic blood vessels such as the aorta. Elastin is also very important in the lungs, elastic ligaments, the skin, the bladder, elastic cartilage, and the intervertebral disc above the sacroiliac. It is present in all vertebrates above the jawless fish [1].
[edit] See also
[edit] External links
Protein: fibrous proteins | |
|---|---|
| Collagen | Type-I (COL1A1) - Type-II (COL2A1) - Type-III - Type-IV - Type-V - Type XI (COL11A2) - Type-XVII - Type-XVIII |
| Keratin/Cytokeratin | type I (10, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21), type II (1, 2A, 3, 4, 5, 6A, 7, 8, 9), Hair (Type I, Type II), Beta |
| other | Elastin - Cytoskeletal |
es:Elastina it:Elastina nl:Elastine pt:Elastina sr:Еластин sv:Elastin
